The Autoimmune Diseases

Autoimmune Diseases

Prophylaxis of the Autoimmune Diseases

Pasteur’s correct Germ Theory of Disease led to discovery of the Immunity System that exists for defense against diseases caused by bacteria or virus infections. In order to cope with the huge diversity of microbial infections, the immunity system needs a flexibility of immune response. This is provided by use of semi-random somatic gene mutations in lymphocytes, the cells that recognize invadi...

Autoimmune Diseases: The New Frontiers

Immunosuppressive drugs have long been used in the treatment of autoimmune diseases (AD). These drugs such as corticosteroids, methotrexate and cyclophosphamide cause the suppression of the immune system particularly on the T cell activation and inhibition of inflammatory cytokines production. However, patients prescribed with these drugs suffer from reduced immunity. They have increased suscep...

P 86: CD166 as a Therapeutic Target in Autoimmune Diseases

About 3 decades ago CD6 identified as one of the first antigens expresses on the majority of T cells and a subset of B cells. CD6 regulates cellular adhesion migration across the endothelial and epithelial cells. In recent years researches indicate its role in pathogenesis of autoimmune diseases. Many researches have been done in recent years to block CD6 by CD6 mono clonal antibodies, IOR-T1 a...

Air Pollution and its Effects on Autoimmune Diseases